Lola Greeno was born on Cape Barren Island. She later moved to Flinders Island to live. Greeno lived on Flinders until 1972 when she moved to Launceston to improve access to education. In 1997, Greeno completed her Bachelor of Fine Arts at the University of Tasmania in Launceston. Since graduating, Greeno has developed her knowledge and skills though a traineeship at the University of Tasmania Gallery Launceston and as a participant in an internship program at the National Gallery of Australia in Canberra.

Lola Greeno is a well-known Tasmanian Aboriginal  shell worker, sculptor, installation artist and fibre artist  who also works as a curator and is the Program Officer, Aboriginal Arts at Arts Tasmania. Greeno’s work has been exhibited widely throughout Australia including the 2000 Adelaide Biennial Exhibition Beyond the Pale at the Art Gallery of South Australia. Greeno interviewed eleven Tasmanian Aboriginal Elders for the oral History project, As We Remember, Aboriginal Education, Hobart, and worked on the Bringing Them Home project for the National Library of Australia. Greeno’s work is represented in State, National and private collections including the Powerhouse Museum, Sydney, The National Gallery of Australia, Canberra, the  Campbelltown Gallery, NSW, the Queen Victoria Museum and Art Gallery, Launceston, Tasmanian Museum and Art Gallery, Hobart, National Maritime Museum, Sydney, Queensland Art Gallery, Brisbane and the National Museum of Australia, Canberra.